The record

LegislationLegislation· Dec 2025
S 355 Passed Senate — in House

Sponsored by Cory A. Booker (D)

FDA Modernization Act 3.0

Requires FDA to allow alternatives to animal testing for experimental drug applications.

Tradeoff

Implements a 2023 law allowing nonclinical tests instead of animal tests. Takes effect immediately without the usual public comment period.

What's in it

See official bill text

Passed the Senate by on December 16, 2025 — now in the House.

  1. Senate

    Introduced

    (Feb 3, 2025)

  2. Senate

    Committee on Health, Education, Labor, and Pensions(Feb 3, 2025)

  3. Senate · Amended

    Senator Booker's

    Agreed to by (S.Amdt. 4057 · Dec 16, 2025)

    Drops the Secretary's authority to make additional changes to the listed regulations, and combines the replacement and definition requirements into one paragraph.

    No individual votes were recorded.

  4. Senate

    Passage of the bill

    Passed by (Dec 16, 2025)

    No individual votes were recorded.

  5. Senate

    Taken away from the Committee on Health, Education, Labor, and Pensions

    Discharged(Dec 16, 2025)

  6. House

    Received from the Senate

    Received(Dec 17, 2025)